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Sexual health · Men
Prescription ED medication — sildenafil, tadalafil and vardenafil preparations, and Trimix when oral options aren't suitable — prescribed online when clinically appropriate by a US-licensed clinician. From $60 every 4 weeks, charged only once a clinician prescribes.
Plan, provider care included · Cancel anytime
Plans
From$60/mo
If a clinician decides treatment isn't right for you, you're refunded in full.
Erectile dysfunction is the recurring difficulty getting or keeping an erection firm enough for sex. Sildenafil, tadalafil and vardenafil belong to a class of medications called PDE5 inhibitors, which treat erectile dysfunction by increasing blood flow to the penis during sexual stimulation — they don't cause an erection on their own. Pallas connects you with US-licensed clinicians who prescribe them when it's clinically appropriate for you, as needed or as a low daily dose, in a set number of doses per fill. One plan price covers your clinician, ongoing check-ins, care-team messaging, and your medication when prescribed — shipped free in plain packaging from a US-licensed pharmacy.
Prescription medication for erectile dysfunction, prescribed online by a US-licensed clinician when it's clinically appropriate for you. The medications are sildenafil, tadalafil and vardenafil preparations — PDE5 inhibitors, a class that treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation — plus Trimix, an injection prescribed when oral medication isn't suitable. Your plan is one fill of a set number of doses every 4 weeks, with your clinician, check-ins and care-team messaging included.
That's a clinical decision. A US-licensed clinician reviews your health history, your heart and blood-pressure history, your medications and the answers you give about your erections, and decides whether ED medication is appropriate for you — it isn't right for everyone. PDE5 inhibitors aren't taken with nitrates, for example, and your clinician weighs other medications and conditions the same way.
One price with provider care included, and nothing is charged at checkout. Plans start at $60 every 4 weeks for 6 doses of sildenafil + pycnogenol or tadalafil + pycnogenol; 12- and 18-dose fills, daily tadalafil, vardenafil troches and Trimix are priced per fill, up to $199 every 4 weeks. The plan you choose is charged once a clinician prescribes and renews every 4 weeks until you cancel — pause, change your dose count or cancel anytime from your portal. If a clinician decides treatment isn't right for you, you're refunded in full.
Complete a short online intake about your goals, your health, your medications and your erections. A US-licensed clinician reviews it and, if appropriate, prescribes the medication, which a licensed partner pharmacy fills and ships to your door in plain packaging. Nothing is charged unless a clinician prescribes; if they decide treatment isn't right for you, you owe nothing.

What is ED treatment
Erectile dysfunction is the recurring difficulty getting or keeping an erection firm enough for sex. Sildenafil, tadalafil and vardenafil belong to a class of medications called PDE5 inhibitors, which treat erectile dysfunction by increasing blood flow to the penis during sexual stimulation 12 — they don't cause an erection without it. They're taken as needed before sex, or, for tadalafil, as a low dose every day 2. Trimix is an injection prescribed when oral medications aren't suitable. Your clinician chooses the medication, the form and the strength; the pharmacy fills it as one supply of a set number of doses every 4 weeks.
ED medication is prescribed for erectile dysfunction when a US-licensed clinician decides it's appropriate for you. It is not taken with nitrates, and it doesn't work without sexual stimulation.
What it supports
PDE5 inhibitors treat erectile dysfunction by increasing blood flow to the penis during sexual stimulation 12. Prescribed when a clinician decides it's appropriate for you; individual responses vary.
Taken as needed before sex, or as a low daily dose of tadalafil 2 — your clinician chooses the medication and the form that fit how you live.
A set number of doses every 4 weeks — 6, 12 or 18 for the as-needed tablets — adjusted from your portal, with your care team a message away.
The medications
Every plan is one fill every 4 weeks, from $60 to $199, charged only once a clinician prescribes. Pick the medication you'd prefer; a US-licensed clinician decides which, if any, is appropriate for you — and the strength.
Sildenafil, tadalafil and vardenafil preparations taken before sex — orally dissolving tablets and a troche, in a set number of doses per fill.

Sildenafil 80 mg / pycnogenol 50 mg
Sildenafil, a PDE5 inhibitor, with pycnogenol (French maritime pine bark extract) in an orally dissolving tablet, prescribed for erectile dysfunction when clinically appropriate by a US-licensed clinician.
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Tadalafil 20 mg / pycnogenol 25 mg
Tadalafil, a PDE5 inhibitor, with pycnogenol (French maritime pine bark extract) in an orally dissolving tablet, prescribed for erectile dysfunction when clinically appropriate by a US-licensed clinician.
Start with this option
Tadalafil 20 mg / sildenafil 70 mg
Tadalafil and sildenafil, two PDE5 inhibitors, in one orally dissolving tablet, prescribed for erectile dysfunction when clinically appropriate by a US-licensed clinician.
Start with this option
Vardenafil (strength set by your clinician)
Vardenafil, a PDE5 inhibitor, as a troche that dissolves in the mouth, prescribed for erectile dysfunction when clinically appropriate by a US-licensed clinician, who sets the strength.
Start with this optionLow-dose tadalafil taken every day, as a 5 mg tablet or an orally dissolving tablet with caffeine and L-citrulline — 30 per fill.

Tadalafil 5 mg
Low-dose tadalafil, a PDE5 inhibitor, as a once-daily 5 mg tablet, prescribed for erectile dysfunction when clinically appropriate by a US-licensed clinician.
Start with this option
Tadalafil 5 mg / caffeine 55 mg / L-citrulline 50 mg
Low-dose tadalafil, a PDE5 inhibitor, with caffeine and L-citrulline (an amino acid) in a once-daily orally dissolving tablet, prescribed for erectile dysfunction when clinically appropriate by a US-licensed clinician.
Start with this optionTrimix — alprostadil, papaverine and phentolamine — prescribed when oral medications aren't suitable, with injection instructions from your clinician.
What it's prescribed for
ED medication is prescribed only when clinically appropriate by a US-licensed clinician. Individual responses vary.
Answer a few questions about your health and goals — about two minutes. A licensed provider reviews everything 100% online.

If eligible, your provider writes a prescription and medication ships free and discreet from a US-licensed pharmacy — often within a week.

We stay with you the whole way, with regular check-ins and on-demand messaging with your care team.


Pharmacy & safety
Every ED plan starts with a US-licensed clinician. If prescribed, your medication is filled by a US-licensed pharmacy and shipped free, in plain packaging, to your door.
Pallas does not manufacture or compound medication. Compounded medications are prepared by US-licensed compounding pharmacies; the medication you receive may differ in appearance from any product shown on this site.
FAQ
Prescription medication for erectile dysfunction, prescribed online by a US-licensed clinician when it's clinically appropriate for you. The medications are sildenafil, tadalafil and vardenafil preparations — PDE5 inhibitors, a class that treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation — plus Trimix, an injection prescribed when oral medication isn't suitable. Your plan is one fill of a set number of doses every 4 weeks, with your clinician, check-ins and care-team messaging included.
That's a clinical decision. A US-licensed clinician reviews your health history, your heart and blood-pressure history, your medications and the answers you give about your erections, and decides whether ED medication is appropriate for you — it isn't right for everyone. PDE5 inhibitors aren't taken with nitrates, for example, and your clinician weighs other medications and conditions the same way.
One price with provider care included, and nothing is charged at checkout. Plans start at $60 every 4 weeks for 6 doses of sildenafil + pycnogenol or tadalafil + pycnogenol; 12- and 18-dose fills, daily tadalafil, vardenafil troches and Trimix are priced per fill, up to $199 every 4 weeks. The plan you choose is charged once a clinician prescribes and renews every 4 weeks until you cancel — pause, change your dose count or cancel anytime from your portal. If a clinician decides treatment isn't right for you, you're refunded in full.
Complete a short online intake about your goals, your health, your medications and your erections. A US-licensed clinician reviews it and, if appropriate, prescribes the medication, which a licensed partner pharmacy fills and ships to your door in plain packaging. Nothing is charged unless a clinician prescribes; if they decide treatment isn't right for you, you owe nothing.
You tell us your goals, how often you expect to use it and any ED medication you've tried, and we mark a suggestion in the picker — a starting point, not a prescription. Sildenafil, tadalafil and vardenafil are all PDE5 inhibitors; tadalafil is also prescribed as a low daily dose. Your clinician decides which medication and strength, if any, are appropriate for you. The as-needed tablets come in 6, 12 or 18 doses per fill, and you can change the count from your portal.
They're different ways to take the medication. An orally dissolving tablet (ODT) dissolves on the tongue, a troche dissolves between the cheek and gum, and a tablet is swallowed. Your clinician chooses the form and strength that fit you; the medication and how it works are the same class in each case.
Trimix is a compounded injection of three medications — alprostadil, papaverine and phentolamine — injected into the side of the penis before sex. It's prescribed when oral ED medications aren't suitable or haven't been appropriate for you, and only with injection instructions from your clinician. An erection that lasts more than four hours is a medical emergency; your clinician's instructions cover what to do.
Compounded ED preparations — such as the orally dissolving tablets, troches and Trimix — are not FDA-approved. They are prepared by a US-licensed pharmacy for the individual patient when a clinician prescribes them; which forms are compounded is decided per prescription by the pharmacy filling it. That's why every plan starts with a US-licensed clinician who reviews your health history and prescribes only when clinically appropriate.
Tell your clinician everything you take — the intake asks. PDE5 inhibitors aren't taken with nitrates (medications for chest pain such as nitroglycerin, isosorbide mononitrate or isosorbide dinitrate), and your clinician will also weigh alpha blockers, riociguat, HIV antiretrovirals and nitric-oxide supplements. Chest pain during sex, fainting, or vision changes are reasons to stop and seek care.
Usually not. 43 of 50 states are fully asynchronous: you complete the intake online and a US-licensed clinician reviews it by secure message. Arkansas, Mississippi, New Mexico, North Dakota, Rhode Island, South Dakota, and West Virginia, plus Washington, D.C., require one live video visit to start care — if you live there, you'll schedule a short video visit after your intake.
ED treatment by state
AlabamaAlaskaArizonaArkansasCaliforniaColoradoConnecticutDelawareFloridaGeorgiaHawaiiIdahoIllinoisIndianaIowaKansasKentuckyLouisianaMaineMarylandMassachusettsMichiganMinnesotaMississippiMissouriMontanaNebraskaNevadaNew HampshireNew JerseyNew MexicoNew YorkNorth CarolinaNorth DakotaOhioOklahomaOregonPennsylvaniaRhode IslandSouth CarolinaSouth DakotaTennesseeTexasUtahVermontVirginiaWashingtonWashington, DCWest VirginiaWisconsinWyoming
From our members
Real feedback from Pallas members across our programs.
Quotes from Pallas members, shared with permission; names abbreviated for privacy. Testimonials reflect individual experiences — individual results vary.
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The class facts on this page — that sildenafil, tadalafil and vardenafil are PDE5 inhibitors that treat erectile dysfunction by increasing blood flow to the penis during sexual stimulation, that tadalafil is also prescribed as a daily dose, and that these medications are not taken with nitrates — are from MedlinePlus's drug information for the FDA-approved sildenafil and tadalafil products. The compounded preparations Pallas clinicians prescribe (orally dissolving tablets, troches, Trimix) are prepared per patient by US-licensed pharmacies and have not been evaluated by the FDA; nothing on this page is a promise of a result. ED medication is prescribed only when a US-licensed clinician decides it's appropriate. Cash-pay only; not billed to insurance.