Pallas
A white tube of prescription skin cream

Skincare · Compounded prescription creams

Prescription Skincare

Three prescription creams built on tretinoin: a tretinoin cream, an estriol face cream for women in perimenopause and menopause, and a four-active GHK-Cu peptide complex.

Plan, provider care included · Cancel anytime

Three creams

From$69/mo

Pay over time —available at checkout
Start your visit

Nothing is charged until a clinician prescribes.

  • Three creams built on tretinoin, each with niacinamide
  • Prescription actives — tretinoin, estriol, GHK-Cu, niacinamide — compounded into one cream
  • Your skin and health history reviewed by a US-licensed clinician
  • 30 g every 4 weeks, shipped free and discreet from a US-licensed pharmacy
Compounded in the U.S.A.FSA & HSA Eligible

Prescription skincare is a compounded cream built on tretinoin, the retinoid dermatologists prescribe for acne and for fine lines and rough, sun-damaged skin. Pallas offers three: a tretinoin cream, an estriol face cream for women in perimenopause and menopause, and a four-active GHK-Cu peptide complex.

Adults with acne or breakouts, fine lines, uneven texture, or sun-damaged skin who want a prescription cream rather than over-the-counter products. It isn't right for everyone: pregnancy, breastfeeding, and certain skin conditions or allergies are part of every review.

One price with provider care included, and nothing is charged until a clinician prescribes. The tretinoin cream is $79, the estriol face cream is $69, and the GHK-Cu peptide complex is $169, each for 30 g every 4 weeks. Your plan renews every 4 weeks until you cancel.

Complete a short online intake about your skin, your health history, and the goal you want to address. A US-licensed clinician reviews it and, if appropriate, prescribes the cream that fits. A partner pharmacy compounds it and ships it to your door every 4 weeks.

A woman with silver-streaked hair applying night cream at a vanity

What is prescription skincare

Three creams, built on tretinoin

Tretinoin, a retinoid, is the active all three creams share: dermatologists prescribe it for acne and for fine lines and rough, sun-damaged skin. Niacinamide, a form of vitamin B3, is in all three as well. The estriol face cream adds an estrogen for women in perimenopause and menopause; the GHK-Cu peptide complex adds GHK-Cu, a copper peptide, and caffeine. Compounding puts each combination into a single cream.

  • Three creams: tretinoin, estriol face cream, and the GHK-Cu peptide complex
  • Each one built on tretinoin and niacinamide
  • Prescribed for acne, fine lines, uneven tone, and skin changes in menopause
  • 30 g every 4 weeks, shipped free

Your goals

What people come to us for

Fine lines, texture, and acne

The concerns tretinoin is most often prescribed for. The tretinoin cream is where most people start.

Skin changes in menopause

Skin tends to become thinner and drier as estrogen falls. The estriol face cream is prescribed for women in perimenopause and menopause.

Firmness, in one cream

Four actives compounded together, for people who want one cream instead of several: the GHK-Cu peptide complex.

What it's prescribed for

What is prescription skincare prescribed for?

A woman in her forties applying cream to her cheek

Acne, fine lines, and rough texture — the concerns tretinoin is prescribed for.

A swipe of white cream on a slab of pale stone

Prescription actives, compounded into one cream.

A straw sun hat and sunglasses on a linen bench by a window

Every cream here contains tretinoin, so daily sunscreen is part of the routine.

The process

Start prescription skincare in 3 simple steps

Start online and meet your provider

Step
1

Answer a few questions about your health and goals — about two minutes. A licensed provider reviews everything 100% online.

Hands holding a phone showing the Pallas online intake's goals question

Get your medication delivered to your door

Step
2

If eligible, your provider writes a prescription and medication ships free and discreet from a US-licensed pharmacy — often within a week.

A plain kraft shipping box marked Prescription only

Ongoing support and care, every step

Step
3

We stay with you the whole way, with regular check-ins and on-demand messaging with your care team.

A woman smiling at her phone as a message from her provider asks how she is feeling
Glass medication vials on a pharmacy filling line

Pharmacy & safety

Prescription-only. Pharmacy-prepared.

Your cream is compounded for you once it's prescribed, with a new 30 g fill every 4 weeks.

Compounded in state-licensed US pharmacies
Free, discreet shipping

Common questions

Prescription skincare is a compounded cream built on tretinoin, the retinoid dermatologists prescribe for acne and for fine lines and rough, sun-damaged skin. Pallas offers three: a tretinoin cream, an estriol face cream for women in perimenopause and menopause, and a four-active GHK-Cu peptide complex.

Adults with acne or breakouts, fine lines, uneven texture, or sun-damaged skin who want a prescription cream rather than over-the-counter products. It isn't right for everyone: pregnancy, breastfeeding, and certain skin conditions or allergies are part of every review.

One price with provider care included, and nothing is charged until a clinician prescribes. The tretinoin cream is $79, the estriol face cream is $69, and the GHK-Cu peptide complex is $169, each for 30 g every 4 weeks. Your plan renews every 4 weeks until you cancel.

Complete a short online intake about your skin, your health history, and the goal you want to address. A US-licensed clinician reviews it and, if appropriate, prescribes the cream that fits. A partner pharmacy compounds it and ships it to your door every 4 weeks.

Start from your goal. The tretinoin cream (tretinoin and niacinamide) is for fine lines, texture, and acne. The estriol face cream (estriol, tretinoin, and niacinamide) is for women in perimenopause and menopause. The GHK-Cu peptide complex is an anti-aging cream with four actives: tretinoin, GHK-Cu, caffeine, and niacinamide. Pick the one you'd prefer; your clinician decides which, if any, is appropriate for your skin, and can switch you later.

No. Photos are optional. After checkout you can add up to three (front, left, and right) from the Documents page of your Pallas portal, and only your clinician and care team see them.

Every cream here contains tretinoin, which can make skin more sensitive to the sun, so daily sunscreen is part of using any of them. Tretinoin is generally avoided during pregnancy and breastfeeding; tell your clinician if you're pregnant, breastfeeding, or trying to conceive, and they'll decide which cream, if any, is appropriate. Some dryness or peeling is common when starting tretinoin, and your care team is a message away.

No. Each cream is compounded per patient by a state-licensed US compounding pharmacy, and compounded skincare preparations are not FDA-approved. Compounding combines prescription actives that aren't sold together in one product.

From our members

More from our members

Feedback from Pallas members across our programs.

“NAD+ therapy gave me a mental clarity I didn't realize I'd been missing — the afternoon fog is gone. I feel sharper, steadier, and more motivated throughout the day.”
Sarah M.Verified member
“Since starting the treatments, I'm sleeping more deeply and waking up with real energy for the first time in a long while. My workouts feel stronger, and recovery doesn't drag on the way it used to.”
Tanya L.Verified member
“After a few weeks of treatments, my skin looked brighter and more even than it has in years. I feel refreshed, and friends keep asking what I've changed.”
Amanda G.Verified member
“The whole process was easier than I expected — a few questions online, and my clinician followed up the same day.”
Sarah M.Verified member
“Shipping was fast and discreet, and the care team actually answers when I message them.”
David R.Verified member
“I never felt rushed. My provider explained every option and let me decide what fit.”
Jenna K.Verified member
“Checking in is simple, refills arrive on time, and support replies within hours.”
Marcus T.Verified member
“From sign-up to delivery, everything just worked the way it should.”
Alicia P.Verified member

Quotes from Pallas members, shared with permission; names abbreviated for privacy. Testimonials reflect individual experiences — individual results vary.

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