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Skincare · Compounded prescription creams
Three prescription creams built on tretinoin: a tretinoin cream, an estriol face cream for women in perimenopause and menopause, and a four-active GHK-Cu peptide complex.
Plan, provider care included · Cancel anytime
Three creams
From$69/mo
Nothing is charged until a clinician prescribes.
Prescription skincare starts with tretinoin, the retinoid dermatologists have prescribed for decades for acne and for fine lines and rough, sun-damaged skin. Pallas offers three compounded creams built on it. One plan price covers your clinician, ongoing check-ins, care-team messaging, and your cream: 30 g every 4 weeks, shipped free.
Prescription skincare is a compounded cream built on tretinoin, the retinoid dermatologists prescribe for acne and for fine lines and rough, sun-damaged skin. Pallas offers three: a tretinoin cream, an estriol face cream for women in perimenopause and menopause, and a four-active GHK-Cu peptide complex.
Adults with acne or breakouts, fine lines, uneven texture, or sun-damaged skin who want a prescription cream rather than over-the-counter products. It isn't right for everyone: pregnancy, breastfeeding, and certain skin conditions or allergies are part of every review.
One price with provider care included, and nothing is charged until a clinician prescribes. The tretinoin cream is $79, the estriol face cream is $69, and the GHK-Cu peptide complex is $169, each for 30 g every 4 weeks. Your plan renews every 4 weeks until you cancel.
Complete a short online intake about your skin, your health history, and the goal you want to address. A US-licensed clinician reviews it and, if appropriate, prescribes the cream that fits. A partner pharmacy compounds it and ships it to your door every 4 weeks.

What is prescription skincare
Tretinoin, a retinoid, is the active all three creams share: dermatologists prescribe it for acne and for fine lines and rough, sun-damaged skin. Niacinamide, a form of vitamin B3, is in all three as well. The estriol face cream adds an estrogen for women in perimenopause and menopause; the GHK-Cu peptide complex adds GHK-Cu, a copper peptide, and caffeine. Compounding puts each combination into a single cream.
Your goals
The concerns tretinoin is most often prescribed for. The tretinoin cream is where most people start.
Skin tends to become thinner and drier as estrogen falls. The estriol face cream is prescribed for women in perimenopause and menopause.
Four actives compounded together, for people who want one cream instead of several: the GHK-Cu peptide complex.
The creams
From $69 to $169 for 30 g every 4 weeks.
All three pair tretinoin, a retinoid, with niacinamide. The estriol face cream adds an estrogen and is for women; the GHK-Cu peptide complex adds GHK-Cu and caffeine.
What it's prescribed for
Answer a few questions about your health and goals — about two minutes. A licensed provider reviews everything 100% online.

If eligible, your provider writes a prescription and medication ships free and discreet from a US-licensed pharmacy — often within a week.

We stay with you the whole way, with regular check-ins and on-demand messaging with your care team.


Pharmacy & safety
Your cream is compounded for you once it's prescribed, with a new 30 g fill every 4 weeks.
Prescription skincare is a compounded cream built on tretinoin, the retinoid dermatologists prescribe for acne and for fine lines and rough, sun-damaged skin. Pallas offers three: a tretinoin cream, an estriol face cream for women in perimenopause and menopause, and a four-active GHK-Cu peptide complex.
Adults with acne or breakouts, fine lines, uneven texture, or sun-damaged skin who want a prescription cream rather than over-the-counter products. It isn't right for everyone: pregnancy, breastfeeding, and certain skin conditions or allergies are part of every review.
One price with provider care included, and nothing is charged until a clinician prescribes. The tretinoin cream is $79, the estriol face cream is $69, and the GHK-Cu peptide complex is $169, each for 30 g every 4 weeks. Your plan renews every 4 weeks until you cancel.
Complete a short online intake about your skin, your health history, and the goal you want to address. A US-licensed clinician reviews it and, if appropriate, prescribes the cream that fits. A partner pharmacy compounds it and ships it to your door every 4 weeks.
Start from your goal. The tretinoin cream (tretinoin and niacinamide) is for fine lines, texture, and acne. The estriol face cream (estriol, tretinoin, and niacinamide) is for women in perimenopause and menopause. The GHK-Cu peptide complex is an anti-aging cream with four actives: tretinoin, GHK-Cu, caffeine, and niacinamide. Pick the one you'd prefer; your clinician decides which, if any, is appropriate for your skin, and can switch you later.
No. Photos are optional. After checkout you can add up to three (front, left, and right) from the Documents page of your Pallas portal, and only your clinician and care team see them.
Every cream here contains tretinoin, which can make skin more sensitive to the sun, so daily sunscreen is part of using any of them. Tretinoin is generally avoided during pregnancy and breastfeeding; tell your clinician if you're pregnant, breastfeeding, or trying to conceive, and they'll decide which cream, if any, is appropriate. Some dryness or peeling is common when starting tretinoin, and your care team is a message away.
No. Each cream is compounded per patient by a state-licensed US compounding pharmacy, and compounded skincare preparations are not FDA-approved. Compounding combines prescription actives that aren't sold together in one product.
From our members
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Quotes from Pallas members, shared with permission; names abbreviated for privacy. Testimonials reflect individual experiences — individual results vary.
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