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Skincare · Prescription anti-aging cream
GHK-Cu Peptide Complex
An anti-aging cream with four actives: GHK-Cu (a copper peptide), tretinoin, caffeine, and niacinamide. Prescribed for fine lines, uneven tone, and loss of firmness.
Plan, provider care included · Cancel anytime
GHK-Cu peptide complex
$169/mo
Pay over time —available at checkout
Start your visitNothing is charged until a clinician prescribes.
- GHK-Cu 3%, included to support skin firmness, with tretinoin 0.01%, caffeine 1%, and niacinamide
- One prescription cream in place of several separate products
- Your skin and health history reviewed by a US-licensed clinician
- 30 g every 4 weeks, shipped free and discreet from a US-licensed pharmacy
The GHK-Cu peptide complex is an anti-aging cream that combines four actives in one compounded cream: tretinoin, a retinoid; GHK-Cu, a copper peptide made of three amino acids bound to copper; caffeine; and niacinamide, a form of vitamin B3. One plan price covers your clinician, ongoing check-ins, care-team messaging, and your cream: 30 g every 4 weeks, shipped free.
Compounded in the U.S.A.FSA & HSA Eligible
A compounded prescription anti-aging cream that combines four actives: GHK-Cu 3% (a copper peptide), tretinoin 0.01% (a retinoid), caffeine 1%, and niacinamide (a form of vitamin B3). It is prescribed for fine lines, uneven tone, and loss of firmness.
Adults who want one prescription cream for fine lines, texture, and firmness rather than several separate products. It isn't right for everyone: pregnancy, breastfeeding, and certain skin conditions or allergies are part of every review.
One price with provider care included, and nothing is charged until a clinician prescribes. The GHK-Cu peptide complex is $169 every 4 weeks and renews until you cancel.
Complete a short online intake about your skin and your health history. A US-licensed clinician reviews it and, if appropriate, prescribes the cream. A partner pharmacy compounds it and ships it to your door every 4 weeks.
What is the GHK-Cu peptide complex
Four actives, compounded into one cream
Tretinoin is a retinoid that promotes the shedding of surface skin cells 1. GHK-Cu is a copper peptide, three amino acids bound to copper; it occurs naturally in the body and declines with age, and in laboratory studies it increases the collagen and elastin that skin cells make 2. Caffeine and niacinamide, a form of vitamin B3, are used widely in skincare. Compounding puts all four into a single cream.
- GHK-Cu 3%, tretinoin 0.01%, caffeine 1%, and niacinamide in one cream
- One prescription cream in place of several separate products
- Prescribed for fine lines, uneven tone, and loss of firmness
- 30 g every 4 weeks, shipped free
The studies of GHK-Cu are small and less rigorous than tretinoin's, and this cream's tretinoin, at 0.01%, is a low strength.
What's in it
Four actives, one cream
Tretinoin
A retinoid, at 0.01% in this cream. It promotes the shedding of surface skin cells 1.
GHK-Cu
A copper peptide: three amino acids bound to copper, found naturally in the body; 3% in this cream. In lab studies it increases the collagen and elastin skin cells make, and small studies of creams containing it have reported firmer skin and fewer fine lines 2.
Caffeine and niacinamide
Caffeine at 1%, and niacinamide, a form of vitamin B3 used in skincare to support the skin barrier.
What it's prescribed for
Why do people choose the GHK-Cu peptide complex?
Fine lines, texture, and firmness — the goals people bring to this cream.
One cream instead of several — four actives compounded together.
Shipped free, in plain packaging, to your door.
Get your medication delivered to your door
Step
2
If eligible, your provider writes a prescription and medication ships free and discreet from a US-licensed pharmacy — often within a week.
Ongoing support and care, every step
Step
3
We stay with you the whole way, with regular check-ins and on-demand messaging with your care team.
Pharmacy & safety
Prescription-only. Pharmacy-prepared.
Your cream is compounded for you once it's prescribed, with a new 30 g fill every 4 weeks.
Compounded in state-licensed US pharmacies
Free, discreet shipping
Common questions
A compounded prescription anti-aging cream that combines four actives: GHK-Cu 3% (a copper peptide), tretinoin 0.01% (a retinoid), caffeine 1%, and niacinamide (a form of vitamin B3). It is prescribed for fine lines, uneven tone, and loss of firmness.
Adults who want one prescription cream for fine lines, texture, and firmness rather than several separate products. It isn't right for everyone: pregnancy, breastfeeding, and certain skin conditions or allergies are part of every review.
One price with provider care included, and nothing is charged until a clinician prescribes. The GHK-Cu peptide complex is $169 every 4 weeks and renews until you cancel.
Complete a short online intake about your skin and your health history. A US-licensed clinician reviews it and, if appropriate, prescribes the cream. A partner pharmacy compounds it and ships it to your door every 4 weeks.
GHK-Cu is a copper peptide: three amino acids (glycine, histidine, and lysine) bound to copper. It occurs naturally in the body, and levels decline with age. In laboratory studies it increases the collagen and elastin that skin cells make, and studies of cosmetic creams containing it have reported firmer, more elastic skin and fewer fine lines. That research is smaller and less rigorous than tretinoin's, so it is included here to support firmness, not as a promise of a result.
No. It is a cream you apply to your skin. Pallas offers GHK-Cu only as an ingredient in this prescription cream, not as an injection or in any oral form.
It comes in one strength: GHK-Cu 3%, tretinoin 0.01%, and caffeine 1%, with niacinamide. If your clinician thinks a different cream fits your skin better, they can prescribe that instead.
The tretinoin cream contains tretinoin at 0.025%, 0.05%, or 0.1% with niacinamide. The complex contains tretinoin at 0.01% together with GHK-Cu 3% and caffeine 1%.
Follow the directions on your prescription label. A tretinoin cream is usually applied at night to clean, dry skin, with sunscreen every morning. Message your care team with any question about fitting it into your routine.
Tretinoin can make skin more sensitive to the sun, so daily sunscreen is part of using this cream. It is generally avoided during pregnancy and breastfeeding; tell your clinician if you're pregnant, breastfeeding, or trying to conceive, and they'll decide whether it's appropriate. Some dryness, redness, or peeling is common in the first weeks, and your care team is a message away.
No. It is compounded per patient by a state-licensed US compounding pharmacy, and compounded skincare preparations are not FDA-approved. Compounding combines actives that aren't sold together in one product.
No. Photos are optional. After checkout you can add up to three (front, left, and right) from the Documents page of your Pallas portal, and only your clinician and care team see them.
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Sources
The tretinoin facts on this page are from MedlinePlus's drug information for tretinoin topical. The GHK-Cu findings are from a review by the scientist who first identified GHK, written at a skincare company; the laboratory work it describes was done on cells, and the cosmetic-cream studies it summarises are small. Nothing on this page is a promise of a result. This cream is compounded per patient by a US-licensed pharmacy, and compounded preparations are not FDA-approved.