Start online and meet your provider
Step
1
Answer a few questions about your health and goals — about two minutes. A licensed provider reviews everything 100% online.
Recovery · Sermorelin
Sermorelin Injection
Prescribed to support your own growth hormone output. Signals the pituitary the way your natural GHRH does.
- Prompts your own growth hormone release
- A small subcutaneous injection
- Dosing personalized by your clinician
- One plan price, cancel anytime
Growth hormone is your body's repair signal. It's released in pulses, most of it during deep sleep, and it tells your tissues to build muscle protein and burn stored fat for fuel. In healthy men, output falls about 14% with every decade of adult life. Here's the part most people never hear: the gland that makes it usually still works. What fades is the signal from the brain telling it to fire. Sermorelin is a synthetic copy of the active part of that signal, growth hormone-releasing hormone (GHRH). It isn't growth hormone. It prompts your pituitary to release its own, in pulses, with your body's feedback loops still in charge. At Pallas it's a compounded subcutaneous injection with dosing personalized to your health history. One plan price covers your clinician, ongoing check-ins, care-team messaging, and your medication, shipped free and discreet.
Compounded in the U.S.A.FSA & HSA eligible
A copy of the first 29 amino acids of GHRH, your brain's signal to the pituitary. It prompts your own growth hormone release.
Nothing is charged until a clinician prescribes. $139 first month, then $179 every 4 weeks until you cancel; longer plans cost less.
Complete a short online intake. A US-licensed clinician reviews it and, if appropriate, prescribes sermorelin, shipped to your door.
What is sermorelin
The gland still works. The signal got quiet.
Growth hormone is your body's repair signal. It's released in pulses, and in men about 70% of the day's output comes in the first hours of deep sleep.2 It tells your tissues to build muscle protein and burn stored fat for fuel.1 In healthy men, output falls about 14% with every decade of adult life.3 Here's what most people never hear: the pituitary gland that makes it usually still works. What fades is the signal from the brain telling it to fire.6 Sermorelin is that signal, a synthetic copy of the first 29 amino acids of growth hormone-releasing hormone (GHRH), the part your pituitary actually reads.4
The research
What sermorelin is studied for
Muscle and strength
Growth hormone drives the protein synthesis that rebuilds muscle after you train.1 In studies of older men, GHRH(1‑29) and a close analog raised growth hormone, with gains in lean mass and some strength measures.6,7,8
Your overnight repair window
In men, deep sleep and growth hormone fall together between early adulthood and midlife.9 Sermorelin is not a sleep aid. It's prescribed to support the growth hormone pulse that window is built around.
What it supports
Why do people explore sermorelin therapy?
Sterile
CompoundingBatch
TestedParaben
FreeSilicone
FreeNo Artificial
DyesGluten
Free
Get your medication delivered to your door
Step
2
If eligible, your provider writes a prescription and medication ships free and discreet from a US-licensed pharmacy — often within a week.
Ongoing support and care, every step
Step
3
We stay with you the whole way, with regular check-ins and on-demand messaging with your care team.
Pharmacy & safety
Prescription-only. Pharmacy-prepared.
Your medication is prepared for you once it's prescribed, then shipped to your door.
Compounded in state-licensed US pharmacies
Free, discreet shipping
Common questions
A copy of the first 29 amino acids of GHRH, your brain's signal to the pituitary. It prompts your own growth hormone release.
Nothing is charged until a clinician prescribes. $139 first month, then $179 every 4 weeks until you cancel; longer plans cost less.
Complete a short online intake. A US-licensed clinician reviews it and, if appropriate, prescribes sermorelin, shipped to your door.
Prescribed to support your own growth hormone output. In short studies of GHRH(1-29), growth hormone rose and some participants gained lean mass; sleep quality did not change. Results vary.
No. Sermorelin is not growth hormone and not an HGH replacement. It works upstream, prompting your pituitary to release its own growth hormone in pulses, with your body's feedback loops in charge.
Yes. A US-licensed clinician can prescribe sermorelin through telehealth, and state-licensed US compounding pharmacies prepare it. Certain conditions mean it isn't an appropriate treatment.
Most often brief flushing, or soreness, redness or swelling where you inject; headache, dizziness and nausea less often. Seek care right away for signs of an allergic reaction.
That's your clinician's call. The program is for adults 18 to 55; pregnancy or breastfeeding, active cancer, pituitary disease, untreated hypothyroidism, uncontrolled diabetes or heart failure rule it out.
No. Compounded sermorelin is prepared per-patient by state-licensed US compounding pharmacies and is not FDA-approved.
Sermorelin by state
AlabamaAlaskaArizonaArkansasCaliforniaColoradoConnecticutDelawareFloridaGeorgiaHawaiiIdahoIllinoisIndianaIowaKansasKentuckyLouisianaMaineMarylandMassachusettsMichiganMinnesotaMississippiMissouriMontanaNebraskaNevadaNew HampshireNew JerseyNew MexicoNew YorkNorth CarolinaNorth DakotaOhioOklahomaOregonPennsylvaniaRhode IslandSouth CarolinaSouth DakotaTennesseeTexasUtahVermontVirginiaWashingtonWashington, DCWest VirginiaWisconsinWyoming
From our members
More from our members
Feedback from Pallas members across our programs.
Quotes from Pallas members, shared with permission; names abbreviated for privacy. Testimonials reflect individual experiences — individual results vary.
Sermorelin Injection
$139 first month
- Cancel anytime
- Free expedited shipping
- FSA & HSA eligible
- Care-team messaging included
Sources
Compounded sermorelin is not FDA-approved. The studies below describe growth hormone physiology and small, short trials of GHRH(1-29) and a close analog, mostly in adults over 55. They illustrate how the hormone and the drug class work in general; they are not evidence that compounded sermorelin, or any specific formulation or treatment program, will produce the same or any particular result for you. Individual results vary.
- Møller N, Jørgensen JOL. Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects. Endocr Rev. 2009;30(2):152-177.
- Van Cauter E, Plat L, Copinschi G. Interrelations between sleep and the somatotropic axis. Sleep. 1998;21(6):553-566.
- Iranmanesh A, Lizarralde G, Veldhuis JD. Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men. J Clin Endocrinol Metab. 1991;73(5):1081-1088.
- Prakash A, Goa KL. Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency. BioDrugs. 1999;12(2):139-157.
- Walker RF. Sermorelin: a better approach to management of adult-onset growth hormone insufficiency? Clin Interv Aging. 2006;1(4):307-308.
- Corpas E, Harman SM, Piñeyro MA, Roberson R, Blackman MR. Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men. J Clin Endocrinol Metab. 1992;75(2):530-535.
- Khorram O, Laughlin GA, Yen SS. Endocrine and metabolic effects of long-term administration of [Nle27]growth hormone-releasing hormone-(1-29)-NH2 in age-advanced men and women. J Clin Endocrinol Metab. 1997;82(5):1472-1479.
- Vittone J, Blackman MR, Busby-Whitehead J, et al. Effects of single nightly injections of growth hormone-releasing hormone (GHRH 1-29) in healthy elderly men. Metabolism. 1997;46(1):89-96.
- Van Cauter E, Leproult R, Plat L. Age-related changes in slow wave sleep and REM sleep and relationship with growth hormone and cortisol levels in healthy men. JAMA. 2000;284(7):861-868.