Hormone Therapy for Women

Hormone therapy replaces some of the estrogen the body makes less of through perimenopause and menopause. At Pallas it's prescribed as estradiol (a clear olive-oil topical, a cream, or a transdermal patch) or estriol (a vaginal cream) to help manage symptoms like hot flashes, night sweats, disrupted sleep, mood changes, and vaginal dryness.

Women navigating perimenopause or menopause — including surgical menopause or menopause symptoms after a hysterectomy — whose symptoms a clinician decides are appropriate to treat with estrogen. It isn't right for everyone: your history, including any history of blood clots, stroke, or breast, uterine, or ovarian cancer, is part of every review.

One price with provider care included, and nothing is charged until a clinician prescribes. Each form is a 12-week supply: Estradiol clear topical is $199, Estradiol cream and Estradiol patch are $269, and Estriol vaginal cream is $249 — every 12 weeks, renewing until you cancel.

Complete a short online intake about your symptoms, history, and the form you'd prefer. A US-licensed clinician reviews it and, if appropriate, prescribes the form that fits you — it ships to your door as a 12-week supply.

Pick the one you'd prefer to use — a clear olive-oil topical, a cream, a patch, or a vaginal cream — and your clinician decides which, if any, is appropriate for your symptoms and history. Vaginal estriol cream is a local preparation typically considered for vaginal dryness and discomfort; the estradiol forms are systemic. Your care team is a message away if you want to talk it through.

Pallas prescribes estrogen only — estradiol or estriol — and doesn't currently prescribe progesterone. For women who still have a uterus, systemic estrogen (the clear topical, cream, or patch) is generally prescribed together with a progestogen to protect the uterine lining, so your clinician may decide an estrogen-only plan isn't the right fit for you and explain what to ask your own doctor for instead. Vaginal estriol cream is a local preparation and is typically considered without one. If you already take progesterone from another prescriber, tell your clinician in the intake.

Estrogen therapy carries known risks — including blood clots, stroke, and certain cancers — as well as potential benefits, and whether it's right for you depends on your health history. A US-licensed clinician reviews your history and symptoms before prescribing, and we ask you to keep your primary care provider informed and up to date with regular checkups and blood work.

Not necessarily — the clinician decides based on your history. If you have recent hormone-related lab work, you can upload it from your Pallas portal after checkout so your clinician can review it.

Your prescription is filled by a US-licensed pharmacy in the form your clinician prescribes. Some forms are compounded — prepared per-patient by a state-licensed compounding pharmacy — and compounded hormone preparations, including estriol, are not FDA-approved.