Hormone therapy for menopause, prescribed online in South Dakota

Is online hormone therapy available in South Dakota?

Yes. Pallas serves South Dakota and all 50 states plus Washington, D.C.. Every clinician who treats South Dakota patients holds an active license from the South Dakota Board of Medical and Osteopathic Examiners, and partner pharmacies ship to every South Dakota ZIP code. South Dakota requires one live video visit to start care.

What hormone therapy is

Through perimenopause and menopause the ovaries make less estrogen, and the drop is what drives hot flashes, night sweats, broken sleep, mood swings, and vaginal dryness for many women. Hormone therapy is prescription estradiol or estriol — through the skin as a cream or a patch, or applied locally as a vaginal cream — usually paired with progesterone for women who have a uterus, prescribed to help manage those symptoms.

For women who still have a uterus, systemic estrogen is generally prescribed together with a progestogen to protect the uterine lining. Pallas prescribes progesterone — in the Biest cream, which combines it with estrogen, and as capsules — and your clinician decides which plan, if any, fits your history. The estradiol vaginal cream is a local preparation and is typically considered without one.

Forms, safety, and risks are on the hormone therapy program page.

South Dakota pricing at a glance

• Biest + progesterone cream$269 every 12 weeks · charged once a clinician prescribes
• Progesterone capsules$129 every 12 weeks · charged once a clinician prescribes
• Estradiol patch$399 every 12 weeks · charged once a clinician prescribes
• Estradiol vaginal cream$229 every 12 weeks · charged once a clinician prescribes

• US-licensed clinician review — prescribed only when clinically appropriate
• Ongoing check-ins and care-team messaging in the Pallas app or patient portal
• Free shipping to any South Dakota address (2–3 business days)
• Nothing charged until a clinician prescribes
• Cancel anytime, self-serve

How it works in South Dakota

1. 1

   Complete the online intake

   About five minutes — your symptoms, health history, and the form you'd prefer. Nothing is charged at checkout.

2. 2

   One live video visit, as South Dakota requires

   You book it after checkout. The clinician decides which form, if any, is appropriate, and everything after that first visit is by secure message.

3. 3

   If prescribed, your first 12-week supply ships

   Your first term is charged only once a clinician prescribes, and a US-licensed pharmacy ships it free to your South Dakota address (2–3 business days).

Telehealth rules for hormone therapy in South Dakota

Prescribing for a resident of South Dakota requires a clinician licensed there, and every Pallas clinician who treats South Dakota patients holds an active license from the South Dakota Board of Medical and Osteopathic Examiners. Estradiol, estriol, and progesterone are not controlled substances, so the controlled-substance telemedicine rules don't apply; South Dakota does require one live video visit to establish the provider-patient relationship before a first prescription, and ongoing care continues by secure message. Your prescription is filled by a US-licensed pharmacy, and some forms are compounded per-patient under FDCA §503A.

Nurse practitioner prescribing in South Dakota: Independent after 1,040 licensed CNP practice hours; written collaborative agreement with a physician, CNP, or CNM required until then (SDCL 36-9A-12; SDCL 36-9A-13.1; ARSD 20:62:03:08; verified 2026-08-03).

Also from Pallas: estriol face cream

A separate prescription cream for the face, not a form of hormone therapy: estriol, tretinoin, and niacinamide in one compounded cream, prescribed for the drier, thinner, less elastic skin that comes as estrogen falls. It has its own short intake. From $69.